'AMD and DR Drug Market Will Reach $6.25 billion in 2015' Predicts new Visiongain Report
LONDON, November 5, 2012 /PRNewswire/ --
A new report by visiongain predicts that the world market for AMD and DR drugs will reach $6.25bn in 2015. That revenue forecast and others appear in Macular Degeneration (AMD) and Diabetic Retinopathy (DR): World Drug Market 2013-2023, published in November 2012. Visiongain is a business information provider based in London, UK.
Regeneron's 2011 launch of Eylea (aflibercept) has stimulated the market, proving to be one of the most successful biopharmaceutical launches so far. Eylea is in a three-way battle with Lucentis (ranibizumab; Roche/Novartis) and Avastin (bevacizumab; Roche) for the wet AMD market. Also, the R&D pipeline is strong.
Visiongain's study identifies key pipeline candidates including new anti-vascular endothelial growth factor (VEGF) drugs such as Allergan's DARPin, with an extended duration of action, and new eye drop formulations such as Alcon's ESBA1008 and Ohr's Squalamine. Beyond anti-VEGF drugs, the wet AMD pipeline is headed by Ophthotech Corporation's Fovista, a PDGF-B blocker which achieved high efficacy results in phase II as part of a combination therapy. However, the dry AMD and DR segments have even greater market growth possibilities, the report notes.
James Evans, pharmaceutical industry analyst in visiongain, said: "The DR market has been galvanised by the approval of Lucentis and Alimera's Iluvien in 2012, and there's plenty of room for growth in that segment. A 2011 study suggested that over 100 million people worldwide have DR, and over 21 million of them have diabetic macular oedema (DME), so that's a huge patient population.
"The real unmet need, though, is dry AMD, where there are still no drug treatment options. MacuCLEAR have reached phase III trials, and Alcon completed a phase III trial of Tandospirone in 2012. Beyond that, there's a massive range of approaches being tried, including blocking the complement cascade and modulating the visual cycle, on to things like neuroprotectants and regenerative medicine. Advanced Cell Technology's trial in dry AMD is now the leading embryonic stem cell candidate therapy in the clinic.
"In wet AMD, Eylea has made a massive impact, and looks likely to take nearly a third of the whole AMD and DR market by 2015. It isn't incredibly different to Lucentis, but has even greater VEGF-binding affinity and is a significant salvage option. A lot will come down to whether Bayer can get Eylea to mount the same challenge to Lucentis outside the US, with EU and Japan approvals coming in September 2012, and how fast Eylea can add new indications. Lucentis will be the first into most of the retinal submarkets, like central retinal vein occlusion. But the evidence so far is Eylea is a very competitive alternative, once it catches up."
The study forecasts that the AMD and DR market will continue to expand rapidly to 2023, with wet AMD treatment moving beyond anti-VEGF monotherapy, and treatment options emerging for the first time in dry AMD and DR.
Visiongain's report shows revenue forecasts to 2023 at overall world market, therapeutic submarket, product and national level. It forecasts these world-level submarkets:
- Wet AMD
- Dry AMD
The investigation predicts revenues of leading drugs in the retinal disorders market: Lucentis, Eylea and Avastin. Research, data and analyses cover activities of Roche, Novartis, Pfizer, Regeneron, Allergan and other pharmaceutical companies.
That study discusses R&D and commercial news, shows research interviews and predicts revenues to 2023 in leading national markets. The work analyses the US, Japan, Germany, France, UK, Spain, Italy and the BRIC group.
Macular Degeneration (AMD) and Diabetic Retinopathy (DR): World Drug Market 2013-2023 adds to visiongain's range of analytical reports on industries and markets in healthcare.
For sample pages and further information concerning the visiongain report Macular Degeneration (AMD) and Diabetic Retinopathy (DR): World Drug Market 2013-2023 please visit http://www.visiongain.com/Report/924/Macular-Degeneration-%28AMD%29-and-Diabetic-Retinopathy-%28DR%29-World-Drug-Market-2013-2023
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Tel: +44 (0) 20 7336 6100
Advanced Cell Technology
AMD Alliance International
American Academy of Ophthalmology (AAO)
American Society of Retina Specialists (ASRS)
Applied Genetic Technologies
Association for Research in Vision and Ophthalmology (ARVO)
Bausch & Lomb
Bayer Yakuhin (Bayer subsidiary)
Casey Eye Institute at Oregon Health and Science University
Chengdu Kanghong Biotech
European Court of Justice
European Medicines Agency (EMEA/EMA)
Food and Drug Administration (US FDA)
Human Genome Sciences
Innovations in Sight
Institute of Ocular Pharmacology
John Hopkins University
Kaplan Medical Center
Lions Eye Institute
Ludwig-Maximilians - University of Munich
Merck & Co.
National Eye Institute (US)
National Institute for Health and Clinical Excellence (NICE, UK)
National Institutes of Health (NIH, US)
Numoda Capital Innovations
Oklahoma Medical Research Foundation
Österreichische Agentur für Gesundheit und Ernährungssicherheit, AGES
Pele Nova Biotecnologica
Pharmaceutical Research and Manufacturers of America (PhRMA)
Prevent Blindness America
Retina Macula Institute
Sanwa Kagaku Kenkyusho
Singapore Eye Research Institute (SERI)
Singapore National Eye Centre
Stemedica Cell Technologies
Teva Pharmaceutical Industries
University College London (UCL)
University of California, Los Angeles
University of Florida
University of Kentucky College of Medicine
University of Michigan
Valeant Pharmaceuticals International
World Health Organization (WHO)
Visiongain is one of the fastest growing and most innovative independent media companies in Europe. Based in London, UK, visiongain produces a host of business-2-business conferences, newsletters, management reports and e-zines focusing on the Energy, Telecoms, Pharmaceutical, Defence, Materials sectors.
Visiongain publishes reports produced by its in-house analysts, who are qualified experts in their field. Visiongain has firmly established itself as the first port-of-call for the business professional, who needs independent, high quality, original material to rely and depend on.
Notes for Editors
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